The neural basis of psychosis in Parkinson’s disease.

Developing targets for understanding current treatments and developing novel treatments The aim of this pharmachological intervention is to implement and enhance a neuroimaging protocol to test for whole brain impairment in PD patients with and without psychosis to (i) enhance understanding of the neural basis of PD psychosis, (ii) estimate the magnitude of impairment both in predefined brain regions and across brain networks and (iii) test for drug effects (5-HT2a inverse agonism) in these networks.

Marcella Montagnese
Marcella Montagnese
Research Fellow

My research interests include the application of neuroimaging (fMRI, DWI, EEG) and graph theory to the study of psychopathology and dementia. I mainly work on psychosis both in neurodegenerative disorders such as Parkinson’s Disease, as well as in schizophrenia. My recent work focuses on using Artificial Intelligence for early dementia detection and prognosis.