Validating data-driven population-reference models (Braincharts, Bethlehem et al., Nature, 2022) with neuroimaging and clinical records for disease stratification and prognosis in neurodegenerative cohorts.
This work involves analyzing neuroimaging and clinical data from memory clinics at Addenbrooke’s Hospital and other NHS trusts around the UK, using artificial intelligence (AI) and normative models to develop individualized tools for patient stratification and prognostication in dementia.